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generic cialis 5mg Table 1 Adverse Reactions in 5 of ARIKAYCE treated MAC Patients and More Frequent than Background Regimen Alone in Trial 1 Adverse Reaction ARIKAYCE plus Background Regimen n 223 n Background Regimen Alone n 112 n Dysphonia a 105 47 1 1 Cough b 87 39 19 17 Bronchospasm c 64 29 12 11 Hemoptysis 40 18 14 13 Ototoxicity d 38 17 11 10 Upper airway irritation e 37 17 2 2 Musculoskeletal pain f 37 17 9 8 Fatigue and asthenia 36 16 11 10 Exacerbation of underlying pulmonary disease g 33 15 11 10 Diarrhea 28 13 5 5 Nausea 26 12 4 4 Pneumonia h 22 10 9 8 Headache 22 10 5 5 Pyrexia 16 7 5 5 Vomiting i 15 7 4 4 Rash j 14 6 2 2 Weight decreased 14 6 1 1 Change in sputum k 12 5 1 1 Chest discomfort 12 5 3 3 a Includes aphonia and dysphonia b Includes cough, productive cough and upper airway cough syndrome c Includes asthma, bronchial hyperreactivity, bronchospasm, dyspnea, dyspnea exertional, prolonged expiration, throat tightness, wheezing d Includes deafness, deafness neurosensory, deafness unilateral, dizziness, hypoacusis, presyncope, tinnitus, vertigo e Includes oropharyngeal pain, oropharyngeal discomfort, throat irritation, pharyngeal erythema, upper airway inflammation, pharyngeal edema, vocal cord inflammation, laryngeal pain, laryngeal erythema, laryngitis f Includes back pain, arthralgia, myalgia, pain body aches, muscle spasm and musculoskeletal g Includes COPD, infective exacerbation of COPD, infective exacerbation of bronchiectasis h Includes atypical pneumonia, empyema, infection pleural effusion, lower respiratory tract infection, lung infection, lung infection pseudomonas, pneumonia, pneumonia aspiration, pneumonia pseudomonas, pseudomonas infection and respiratory tract infection i Includes vomiting and post tussive vomiting j Includes rash, rash maculo papular, drug eruption and urticaria k Includes increased sputum, sputum purulent and sputum discolored

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